Young adults suffer from high educational load when studying at the medical university. University training proceeds under the dynamically changing conditions. Psychological discomfort, low physical activity, noncompliance with the principles of rational nutrition, harmful habits can negatively affect both students’ physical health and their academic performance. The review of scientific papers published in the international and Russian databases, E-Library, PubMed, Cyberleninka, in 2019–2024 is provided. Analysis of the papers will allow us to choose the best health preservation practices. Information about the correlation between behavioral factors, academic performance and health of medical students is essential for prevention programming. The development of exercises considering personal preferences in physical activity can positively affect academic performance, reduce psycho-emotional discomfort, thereby reducing the risk of professional burnout after graduation from the university.