Author contribution: Drugova ED ― material collection and processing, manuscript writing, statistical analysis; Sheina NI ― research concept and design, manuscript writing, editing; Korolik VV ― research concept, manuscript editing.

Compliance with ethical standards: animal keeping and handling during the experiment were compliant with the principles of Good Laboratory Practice (GLP) and GOST 33044―2014 “Principles of Good Laboratory Practice”. The study was approved by the Ethics Committee of the Pirogov Russian National Research Medical University (protocol No. 9 dated September 20, 2023. Blood collection from the volunteers, who had had submitted the informed consent, was regulated by GOST R 59778―2021 “Procedure of Venous and Capillary Blood Sampling Procedure for Laboratory Testing”.