2025 / 04

DOI: 10.24075/rbh.2025.144
Copyright: © 2025 by the authors. Licensee: Pirogov University.
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (CC BY).

ORIGINAL RESEARCH

Comparison of uterine body cancer incidence among women living in environmentally disadvantaged areas (2000−2019)

Kryukova AE1 , Korsakov AV2 , Troshin VP1 , Milushkina OYu2 , Pivovarov YuP2 , Korolik VV2
About authors

1 Bryansk State Technical University, Bryansk, Russia

2 Pirogov Russian National Research Medical University, Moscow, Russia

Correspondence should be addressed: Anna E. Kryukova
Boulevard 50 let Oktyabrya, 7, Bryansk, 241035, Russia; ur.kb@annaavokuyrk

About paper

Acknowledgement: the authors thank A.I. Maklashova, Chief Medical Officer at the Bryansk Regional Oncological Dispensary, for providing anonymized statistical information on the incidence of endometrial cancer in women in the cities and districts of the Bryansk region for the period from 2000 to 2019.

Author contribution: Kryukova AE ― literature search, statistical processing, authoring, editing, and discussion of the article; Korsakov AV ― analysis of literary data, concept and design of the study, interpretation of the results, approval of the final version of the article; Troshin VP ― data analysis and interpretation, authoring, editing, and discussion of the article; Milushkina OYu ― analysis of literary data, analysis and interpretation of data, editing and discussion of the article; Pivovarov YuP, Korolik VV ― analysis and interpretation of data, editing and discussion of the article.

Compliance with ethical standards: the study used anonymized statistical information on the incidence of UBC in the Bryansk region in 2000–2019.

Received: 2025-04-18 Accepted: 2025-10-16 Published online: 2025-12-22
|
  1. Bray F, Laversanne M, Sung H, Ferlay J, Siegel RL, Soerjomataram I, et al. Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2024; 74 (3): 229−63. DOI: 10.3322/caac.21834.
  2. Kaprin AD, Starinskij VV, Shahzadova AO. Sostojanie onkologicheskoj pomoshhi naseleniju Rossii v 2022 godu. M.: MNIOI im. P. A. Gercena — filial FGBU "NMIC radiologii" Minzdrava Rossii, 2023; 236 p. (in Rus.).
  3. Dutta S, Gorain B, Choudhury H, Roychoudhury S, Sengupta P. Environmental and occupational exposure of metals and female reproductive health. Environ SciPollut Res Int. 2022; 29 (41): 62067−92. DOI: 10.1007/s11356-021-16581-9.
  4. Nasiadek M, Kilanowicz A, Darago A, Lazarenkow A, Michalska M. The effect of cadmium on the coagulation and fibrinolytic system in women with uterine endometrial cancer and myoma. Int J Occup Med Environ Health. 2013; 26 (2): 291−301. DOI: 10.2478/s13382-013-0089-z.
  5. Utada M, Brenner AV, Preston DL, Cologne JB, Sakata R, Sugiyama H, et al. Radiation risks of uterine cancer in atomic bomb survivors: 1958−2009. JNCI Cancer Spectr. 2018; 2 (4): pky081. DOI: 10.1093/jncics/pky081.
  6. Ivanova MK, Shajfutdinova GM, Ivanova AJu. Analiz vzaimosvjazi onkologicheskoj zabolevaemosti zlokachestvennymi novoobrazovanijami reproduktivnoj sistemy u zhenshhin Udmurtii ot pokazatelej zagrjaznenija atmosfernogo vozduha. Mezhdunarodnyj zhurnal prikladnyh i fundamental'nyh issledovanij. 2018; 5 (ч. 2): 339−43 (in Rus.).
  7. Lazarev AF, Lubennikov VA, Putilova AA, Gubina GG. Zabolevaemost' zlokachestvennymi novoobrazovanijami naselenija jugo-zapadnyh rajonov Altajskogo kraja i puti snizhenija kancerogennogo riska. Polzunovskij vestnik. 2005; (4): 80−2 (in Rus.).
  8. Kudencova GV. Vlijanie antropogennyh faktorov na razvitie zlokachestvennyh novoobrazovanij v Kurskoj oblasti. Zdorov'e naselenija i sreda obitanija — ZNiSO. 2007; (1): 19−23 (in Rus.).
  9. Sitdikova ID, Ivanova MK. Gigienicheskaja ocenka i upravlenie faktorami riska kancerogennoj i mutagennoj opasnosti v uslovijah sovremennogo tehnogeneza. Zdorov'e naselenija i sreda obitanija — ZNiSO. 2013; (4): 11−3 (in Rus.).
  10. Izrajel JuA, Bogdevich IM. Atlas sovremennyh i prognoznyh aspektov posledstvij avarii na Chernobyl'skoj AJeS na postradavshih territorijah Rossii i Belarusi. M.; Minsk: Infosfera, 2009; 140 p. (in Rus.).
  11. Jablokov AV, Nesterenko VB, Nesterenko AV, Preobrazhenskaja NE. Chernobyl': posledstvija Katastrofy dlja cheloveka i prirody. 6-e izd., dop. i pererab. M.: Tovarishhestvo nauchnyh izdanij KMK, 2016; 826 p. (in Rus.).
  12. Jahrjushin VN. Dannye po radioaktivnomu zagrjazneniju territorii naselennyh punktov Rossijskoj Federacii ceziem-137, stronciem-90 i plutoniem-239+240. Obninsk: FGBU "NPO "Tajfun", 2023; 228 p. (in Rus.). Available from: https://www.rpatyphoon.ru/upload/medialibrary/ezhegodniki/rzrf/ezheg_rzrf_2023.pdf.
  13. Romanovich IK, Bruk GJa, Bazjukin AB, Bratilova AA, Jakovlev VA. Dinamika srednih godovyh i nakoplennyh doz obluchenija vzroslogo naselenija Rossijskoj Federacii posle avarii na Chernobyl'skoj AJeS. Zdorov'e naselenija i sreda obitanija — ZNiSO. 2020; (3): 33–8 (in Rus.).
  14. Trapeznikova LN. Dozy obluchenija naselenija Brjanskoj oblasti ot razlichnyh istochnikov ionizirujushhego izluchenija za 2020 god (informacionnyj spravochnik). Brjansk: Upravlenie Federal'noj sluzhby po nadzoru v sfere zashhity prav potrebitelej i blagopoluchija cheloveka po Brjanskoj oblasti, 2021; 51 p. (in Rus.).
  15. Goroda i rajony Brjanskoj oblasti (statisticheskij sbornik). Brjansk: Upravlenie Federal'noj sluzhby gosudarstvennoj statistiki po Brjanskoj oblasti, 2020; 255 p. (in Rus.).
  16. Gosudarstvennyj doklad "O sostojanii i ob ohrane okruzhajushhej sredy Rossijskoj Federacii v 2021 godu". M.: Minprirody Rossii; MGU im. M.V.Lomonosova, 2023; 686 p. (in Rus.).
  17. Korsakov AV, Geger EV, Lagerev DG, Pugach LI, Mousseau TA. De novo congenital malformation frequencies in children from the Bryansk region following the Chernobyl disaster (2000–2017). Heliyon. 2020; (6): 8. DOI: 10.1016/j.heliyon.2020.e04616.
  18. Korsakov AV, Golovleva AA, Troshin VP, Lagerev DG, Pugach LI. Ovarian malignancies frequency in the female population from the Bryansk region living in conditions of radioactive, chemical and combine contamination (2000–2020). Life (Basel). 2021; 11 (11): 1272. DOI: 10.3390/life11111272.
  19. Korsakov AV, Kryukova AЕ, Troshin VP, Milushkina ОY, Lagerev DG. Cervical and endometrial cancer incidence in the female population from the Bryansk region living in conditions of chemical, radioactive and combined environmental contamination (2000–2020). Life (Basel). 2022; 12 (10): 1488. DOI: 10.3390/life12101488.
  20. Jablokov AV. O koncepcii populjacionnogo gruza (obzor). Gigiena i sanitarija. 2015; (6): 11−4 (in Rus.).
  21. Pervichnaja zabolevaemost' zhenskogo naselenija zlokachestvennymi novoobrazovanijami jaichnikov za 2000−2019 gg. Materialy Brjanskogo oblastnogo onkologicheskogo dispansera. Brjansk, 2021. (In Rus.).
  22. Yang HP, Brinton LA, Platz EA, Lissowska J, Lacey JV Jr, Sherman ME, et al. Active and passive cigarette smoking and the risk of endometrial cancer in Poland. Eur J Cancer. 2010; 46 (4): 690−6. DOI: 10.1016/j.ejca.2009.11.015.
  23. Rieck G, Fiander A. The effect of lifestyle factors on gynaecological cancer. Best Pract Res Clin Obstet Gynaecol. 2006; 20 (2): 227−51. DOI: 10.1016/j.bpobgyn.2005.10.010.
  24. Shishkina OG, Privalenko VV. Tehnogennaja nagruzka kak faktor riska raka tela matki u zhenshhin raznogo vozrasta v Rostovskoj oblasti. Glavnyj vrach juga Rossii. 2011; 4 (27): 7−11 (in Rus.).
  25. Golovleva AA, Korsakov AV, Troshin VP, Milushkina OY, Pivovarov YP, Korolik VV, et al. Comparative assessment of the incidence of malignant neoplasms of the ovaries in women living in the environmentally disadvantaged areas (200-2019). Russian Bulletin of Hygiene. 2024; (4): 27–33. DOI: 10.24075/rbh.2024.114.