ISSN Print 2713-0878
ISSN Online 2713-0886
BIOMEDICAL JOURNAL OF ERMC EASTERN EUROPEAN
Copyright: © 2024 by the authors. Licensee: Pirogov University.
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (CC BY).
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (CC BY).
ORIGINAL RESEARCH
Comparative assessment of the incidence of malignant neoplasms of the ovaries in women living in the environmentally disadvantaged areas (200-2019)
About authors
1 Bryansk State Technical University, Bryansk, Russia
2 Pirogov Russian National Research Medical University, Moscow, Russia
Correspondence should be addressed: Alexandra A. Golovleva
Bulvar 50 let Oktyabrya, 7, Bryansk, 241035, Russia; ur.xednay@avelvologskela
About paper
Acknowledgement: the authors would like to thank A.I. Maklashova, Chief Physician at the Bryansk Regional Oncology Dispensary, for provision of impersonal statistical information about the incidence of MNOs in women in the towns and districts of the Bryansk Region for the years 2000–2019.
Author contribution: Golovleva AA — search for literature, statistical analysis, manuscript writing, editing and discussion; Korsakov AV — literature data analysis, study concept and design, interpretation of the results, approval of the final version of the article; Troshin VP — data analysis and interpretation, manuscript writing, editing and discussion; Milushkina OYu — literature data analysis, data analysis and interpretation, manuscript editing and discussion; Pivovarov YuP, Korolik VV — data analysis and interpretation, manuscript editing and discussion; Lagerev DG — statistical processing, data analysis and interpretation.
Compliance with ethical standards: the study involved the use of impersonal statistical information about the incidence of MNOs in women in the areas of the Bryansk Region for the years 2000–2019.
Received: 2023-11-08
Accepted: 2024-05-10
Published online: 2024-12-24
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Fig. 1. Dynamics of primary incidence of MNOs in women living in environmentally different territories of the Bryansk Region with the long-term trends by 3-year periods for the years 2000–2019 (recalculated per 100,000 population)
Table 1. Ranking of the Bryansk Region territories based on the levels of radioactive, chemical, and combined environmental pollution, and primary incidence of MNOs (2000–2019)
Note: * — difference (%) from the all-Russian level of primary incidence of MNOs (2000–2019). Differences in primary incidence of MNOs based on the Mann–Whitney U test: in environmentally safe territories and territories with chemical (p = 0.67), radioactive (p = 0.22), and combined (p = 0.95) contamination; chemical and radioactive (p = 0.11), chemical and combined (p = 0.94), radioactive and combined (p = 0.30) contamination.
Table 2. Relative risk (RR) of primary incidence of MNOs in women aged 18–80 years living in the territories with varying levels of radioactive, chemical, and combined environmental contamination for the years 2000–2019
Table 3. Comparative assessment of primary incidence of high-grade, intermediate grade, and low-grade MNOs among women aged 41–60 years living in environmentally different territories of the Bryansk Region for the years 2000–2019 (recalculated per 100,000 population)
Note: * — the differences are significant at р < 0.05; ** — the differences are significant at р < 0.001; n/s — the differences are non-significant at р > 0.05.
Table 4. Relative risk (RR) of primary incidence of low-grade MNOs in women aged 41–60 years living in the territories with various levels of radioactive, chemical, and combined contamination of the environment for the years 2000–2019
