Students’ state of health is both a national, and a global challenge. Its relevance is increasing every year. When developing prevention programs, it’s important to consider principal factors of risk for students’ health. The youth is a significant group of population with students being a fundamental part of it. This article analyzes the risk factors that influence students’ state of health to the greatest extent. Bad habits are given considerable attention to. A set of prevention activities must be developed for students taking into account specifics of their education. A comprehensive approach must be used to ensure the greatest effect on students’ health.