Radioactive and chemical contamination can affect carcinogenesis, including the development of malignant neoplasms of the ovaries (MNOs) in women. The study aimed to perform comparative assessment of environmental situation in the towns and districts of the Bryansk Region based on chemical, radioactive, and combined radioactive contamination, as well as primary incidence of MNOs in women in accordance with official statistics for the years 2000–2019. The data for the study were provided by the Bryansk Regional Oncology Dispensary, Bryanskstat, Rostekhnadzor, Rospotrebnadzor. Neither significant differences in primary incidence of MNOs, nor increased risk of MNO were revealed in female population aged 18–80 years, regardless of the environmental conditions of living in 2000–2019. We revealed a significantly elevated relative risk (RR) of primary incidence of low-grade MNOs in women aged 41–60 years living in the environmentally disadvantaged areas compared to women living in the control areas: RR 1.88 (95% CI: 1.43–2.48); p < 0.0001). The rate of low-grade MNOs in women aged 41–60 years in the areas of the combined exposure is 17.6 ± 1.96, which 1.5-fold exceeds the values reported for radioactively contaminated areas (11.7 ± 2.73) and 1.2-fold exceeds the values reported for chemically contaminated areas (15.2 ± 1.31). The combined effects of radioactive and chemical contamination results in the higher RR of low-grade MNOs compared to the areas with only one pollution factor, i.e. radioactive contamination (RR 1.51 (95% CI: 1.00–2.28)), chemical contamination  (RR 1.17 (95% CI: 0.90–1.50)). The findings suggest synergistic effect of radiation and chemical factors on the incidence of low-grade MNOs.
VIEWS 1663
Drinking water occupies one of the leading places among environmental factors responsible for shaping public health, so providing sanitary-and-epidemiologic wellbeing of the population cannot be considered separately from solving the hygienic problem of water supply. The study aimed to provide comparative hygienic characteristics of the quality of drinking water from the Ryazan centralized water supply system based on organoleptic indicators. Comparative assessment of the quality of drinking water was performed based on the analysis of the data of the years of research for the years 2017–2022. We performed analysis of the long-term average annual values of odor at 20 ºС and 60 ºС, taste, color and turbidity, share of samples non-compliant with the hygienic standards, over time. Inidicators were also assessed based on the season of the year and territorial belonging. The average indicator values were compared using analysis of variance; pairwise comparison involved the use of the Scheffe and Tamhane tests considering the Levene’s test results. Confidence intervals of the relative indicators were determined based on the Wilson score. The long-term average annual values of organoleptic indicators of the quality of drinking water in Ryazan are compliant with SanPiN 1.2.3685-21. A small number of samples had odor, taste, and color exceeding the hygienic standards. Turbidity that was non-compliant with the hygienic requirements in 2.2% of samples and reached the maximum value of 16.4 mg/L (kaolin) should be considered the most challenging indicator of the quality of test drinking water.
VIEWS 2096
Great attention is traditionally paid to prevention of infectious diseases in pediatric population. Along with the institutional, therapeutic and preventive measures, it is necessary to control public awareness of such issues. The study was aimed to analyze awareness of primary school, high school, and senior school students, college and university students of the issues related to prevention of infections with fecal-oral and hematogenic transmission mechanisms. The study was carried out using the private online questionnaire consisting of three items (personal information, questions regarding awareness of the infections with fecal-oral and hematogenic transmission mechanisms). The properly filled questionnaires of the respondents, who had given to consent to participation in the study, were analyzed. It was found that schoolchildren aged 12–15 years were the least informed about the issues related to prevention of infections with fecal-oral and hematogenic transmission mechanisms, while the group of students aged 18–30 years was the most informed. It was hypothesized that parents influenced the choice of answer made by schoolchildren aged 6–11 during the online survey. It has been proposed to ensure raising of the 6–15-year-old students’ awareness of the issues related to prevention of infectious diseases, including by means of hygienic training when mastering such school curriculum subjects, as Biology and Human Life Safety.
VIEWS 1674