The issues of damage to health related to the spread of nicotine product consumption are global. At the initiative of the Department of Healthcare Management, Burdenko Voronezh State Medical University, the organizational model of medical measures to overcome nicotine dependence involving formation of the smoking cessation groups among young adults, management and enlightment of the participants on the issues related to damage from nicotine dependence and free provision of the medicines facilitating smoking cessation was implemented. The study was aimed to assess the organizational model effectiveness based on the nicotine cessation rates of young adults. The model participants (42 individuals) were divided into three groups and provided free medicines: tablets containing cytisine in group 1, nicotine sprays in group 2, nicotine patches in group 3. The experiment was conducted for 30 days, during which three follow-up questionnaire surveys were performed. In the experiment, 31.7% of subjects stopped smoking completely, while the total positive effect bringing together those, who ceased smoking, and those, who reduced smoking, was 66.7%. Furthermore, the tablets containing cytisine turned out to be the most effective option. Thus, the study results obtained within the framework of the proposed organizational model can be considered useful in terms of further practical use. It can be recommended to include the model in the target program involving provision of medicines for treatment of nicotine dependence at the expense of the regional budget and attracted funds of enterprises and organizations.