Shaping healthy lifestyle in high school seniors is one of the main challenges of society. The high school seniors' lifestyle is formed under the influence of their parents and teachers. The study was aimed to form a picture of the hygienic profile of high school seniors, their parents and teachers. An online questionnaire survey of 158 high school students aged 15–18, 113 parents, 202 teachers was carried out. It has been found that 88.6% of high school seniors spend much time on electronic gadgets, 37.2% spend more than three hours on homework, 39.9% sleep less than six hours per day, 35.3% drink alcohol, 12.7% have tried smoking, 4.0% smoke, 17.3% spend less than 60 min per day outdoors, 54.3% have insufficient physical activity, 25% do not follow principles of healthy eating, 25.1% eat cooked meals less than two times a day, 11.0% have a late supper. Among parents, spending much time on lectronic gadgets is reported in 30.1%, furthermore, 46.9% of them do nothing to improve their health, 55.7% sleep less than six hours per day, 25.6% drink alcohol, 11.5% smoke, 49.6% have insufficient physical activity, 20.4% do not follow principles of healthy eating, 15.0% have a late supper. As for teachers, spending much time on lectronic gadgets is reported in 37.8%, 41.7% of teachers do nothing to improve their health, 59.2% sleep less than six hours per day, 9.5% drink alcohol, 9.5% smoke, 42.8% have insufficient physical activity, 38.3% do not follow principles of healthy eating, 26.0% have a late supper. The hygienic profile of high school seniors, their parents and teachers demonstrates unhealthy lifestyle choices that pose a challenge for their lifestyle and health.